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On their own, those studies show some promise, but these individual components don’t perform as well on their own as CBD and THC do.21 However, when studies provide participants with more complex CBD formulations that include a full spectrum of cannabinoids, including THC, CBG, CBN, CBC, and all their brothers and sisters, effects typically associated with CBD become more pronounced at lower doses.22 This is the entourage effect in action: When you combine CBD with THC and other effective cannabis constituents, you create an effect that’s greater than the sum of its parts